Vinpocetine
Research reviewed: Up until 03/2026
Vinpocetine is a dietary supplement with 5 published peer-reviewed studies involving 520 participants, researched for Cerebral Blood Flow & Neuroprotection, Cognitive Function & Memory, Safety & Tolerability.
Evidence at a Glance
Strength is scored by study design, sample size, study type, and outcomes
Cerebral Blood Flow & Neuroprotection
ModerateCognitive Function & Memory
ModerateSafety & Tolerability
ModerateResearch Visualised
Visual breakdown of the clinical data.
Study Quality Breakdown
What types of studies were conducted
Participants Per Study
Larger samples = more reliable results
Research Timeline
When the studies were published
All Studies
Detailed breakdown of each trial. Click to expand.
Cerebral Blood Flow & Neuroprotection
To evaluate efficacy and safety of vinpocetine in acute cerebral infarction (CAVIN trial)
Study Type
Randomized, open-label, controlled, multicenter
Purpose
To evaluate efficacy and safety of vinpocetine in acute cerebral infarction (CAVIN trial)
Dose
Vinpocetine intravenous infusion
Participants
Acute cerebral infarction patients
Duration
1-3 months follow-up
Results
Vinpocetine reduced degree of disability in acute ischemic stroke. Transcranial Doppler showed significantly increased cerebral blood flow.
How They Measured It
Cerebral blood flow, disability reduction, neurological outcomes
To investigate effects of vinpocetine on cerebral blood flow and cognitive functions
Study Type
Randomized controlled trial
Purpose
To investigate effects of vinpocetine on cerebral blood flow and cognitive functions
Dose
Oral vinpocetine
Participants
Patients with cognitive decline
Duration
12 weeks
Results
Significant improvement in cognitive functions found after 12-week vinpocetine therapy using psychometric tests.
How They Measured It
Cerebral blood flow, psychometric cognitive tests
Cognitive Function & Memory
To review safety and efficacy of vinpocetine in acute ischemic stroke
Study Type
Systematic review and meta-analysis
Purpose
To review safety and efficacy of vinpocetine in acute ischemic stroke
Dose
Various vinpocetine doses and durations
Participants
Meta-analysis of multiple RCTs
Duration
Various
Results
Vinpocetine reduces combined likelihood of death and disability at 1 and 3 months. Associated with improvement in cognition and quality of life.
How They Measured It
Meta-analysis of RCT data on disability and outcome measures
To assess vinpocetine for cognitive impairment and dementia
Study Type
Cochrane review
Purpose
To assess vinpocetine for cognitive impairment and dementia
Dose
Various doses tested
Participants
Meta-analysis of RCTs in dementia patients
Duration
Various
Results
Although vinpocetine might benefit mild-to-moderate dementia patients, evidence is inconclusive. Trials too small/short with insufficient data.
How They Measured It
Literature synthesis of RCT evidence
Safety & Tolerability
To review an update on vinpocetine: discoveries and clinical implications
Study Type
Review
Purpose
To review an update on vinpocetine: discoveries and clinical implications
Dose
Various doses (10-60 mg/day typical)
Participants
Multiple study populations
Duration
Various
Results
Vinpocetine demonstrates excellent safety and tolerability profile with minimal adverse effects in clinical use.
How They Measured It
Literature synthesis of safety and efficacy data
Frequently Asked Questions
Common questions about Vinpocetine research
There are currently 8 peer-reviewed studies on Vinpocetine (Vinpocetine), involving 520 total participants. Research covers Cerebral blood flow, Cognitive function, Memory. The overall evidence strength is rated as Strong.
The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (5 human studies), and reported outcomes.
Vinpocetine has been researched for: Cerebral blood flow, Cognitive function, Memory. Each area has its own body of evidence which you can explore in the study breakdowns above.
Yes, 5 out of 8 studies are human trials. Human trials carry more weight in our evidence scoring system.
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