Quercetin
Research reviewed: Up until 03/2026
Quercetin is a dietary supplement with 9 published peer-reviewed studies involving 209 participants, researched for Post-Myocardial Infarction Recovery, Blood Pressure & Cardiovascular Risk, Inflammation & Oxidative Stress and 4 more areas.
Evidence at a Glance
Strength is scored by study design, sample size, study type, and outcomes
Post-Myocardial Infarction Recovery
ModerateBlood Pressure & Cardiovascular Risk
ModerateInflammation & Oxidative Stress
WeakAtherosclerosis & Cholesterol
WeakBlood Pressure
ModerateMetabolic Health
WeakAthletic Performance & Recovery
ModerateResearch Visualised
Visual breakdown of the clinical data.
Study Quality Breakdown
What types of studies were conducted
Participants Per Study
Larger samples = more reliable results
Research Timeline
When the studies were published
All Studies
Detailed breakdown of each trial. Click to expand.
Post-Myocardial Infarction Recovery
To evaluate the effect of quercetin supplementation on inflammatory markers and quality of life in post-myocardial infarction patients.
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To evaluate the effect of quercetin supplementation on inflammatory markers and quality of life in post-myocardial infarction patients.
Dose
500 mg/day
Participants
88 post-MI patients
Duration
8 weeks
Results
Serum total antioxidant capacity (TAC) was significantly improved and TNF-α was significantly reduced (p<0.05). Quality of life scores improved. No significant changes in blood pressure or heart rate. Results indicate quercetin may reduce oxidative stress and inflammation following heart attack.
How They Measured It
Total antioxidant capacity (TAC), TNF-α, blood pressure, heart rate, quality of life scores
Blood Pressure & Cardiovascular Risk
To determine the effect of quercetin supplementation on blood pressure in adults with hypertension or elevated blood pressure.
Study Type
Systematic review & meta-analysis
Purpose
To determine the effect of quercetin supplementation on blood pressure in adults with hypertension or elevated blood pressure.
Dose
500-1,000 mg/day
Participants
9 RCTs, 500+ participants
Duration
4-12 weeks
Results
Quercetin produced modest but significant reductions in systolic blood pressure (-2.9 mmHg, 95% CI: -5.7, -0.2) and diastolic blood pressure (-2.1 mmHg). Effect sizes were small and heterogeneity was high across included trials.
How They Measured It
Systolic blood pressure (SBP), diastolic blood pressure (DBP)
To evaluate quercetin's effects on cardiovascular inflammatory markers in women with Type 2 diabetes.
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To evaluate quercetin's effects on cardiovascular inflammatory markers in women with Type 2 diabetes.
Dose
500 mg/day
Participants
72 women with Type 2 diabetes
Duration
10 weeks
Results
Significant improvements in cardiovascular inflammatory markers (TNF-α, hs-CRP) and antioxidant enzyme activity compared to placebo. Modest lipid improvements were also observed. Results support quercetin as an anti-inflammatory agent in diabetic cardiovascular risk management.
How They Measured It
TNF-α, high-sensitivity CRP (hs-CRP), antioxidant enzyme activity, lipids
Inflammation & Oxidative Stress
To assess quercetin's effects on inflammatory biomarkers and oxidative stress in the general adult population.
Study Type
Multiple meta-analyses compiled
Purpose
To assess quercetin's effects on inflammatory biomarkers and oxidative stress in the general adult population.
Dose
500-1,200 mg/day
Participants
18+ RCTs combined
Duration
4-12 weeks
Results
Across compiled meta-analyses (2020-2023), quercetin produced significant reductions in CRP (-0.35-0.5 mg/L) and oxidative stress markers (MDA, TBARS). TNF-α was reduced consistently. IL-6 reductions were variable across trials. Overall evidence supports quercetin as a moderate anti-inflammatory agent.
How They Measured It
CRP, TNF-α, MDA, TBARS, IL-6
Atherosclerosis & Cholesterol
To synthesize evidence on quercetin's effects on atherosclerosis biomarkers including cholesterol.
Study Type
Evidence synthesis & meta-analysis (46 studies)
Purpose
To synthesize evidence on quercetin's effects on atherosclerosis biomarkers including cholesterol.
Dose
500-1,000 mg/day
Participants
Approximately 12 RCTs in clinical subset
Duration
6-12 weeks
Results
Trial sequential analysis confirmed conclusive evidence for reductions in total cholesterol (TC) and LDL-cholesterol. No consistent effects on HDL or triglycerides were found in most RCTs. Results were stronger in populations with elevated baseline cholesterol levels.
How They Measured It
Total cholesterol (TC), LDL-cholesterol, HDL-cholesterol, triglycerides
Blood Pressure
To assess effects of quercetin supplementation on blood pressure
Study Type
Meta-analysis of randomized controlled trials
Purpose
To assess effects of quercetin supplementation on blood pressure
Dose
Quercetin (various doses)
Participants
Meta-analysis of 10 trials with 841 participants
Duration
Various study durations
Results
Quercetin supplementation significantly decreased systolic blood pressure (MD: -2.38 mmHg) in mixed population and in normotensive subgroup (-1.82 mmHg). Diastolic reduction (-3.14 mmHg) in prehypertensive subgroup.
How They Measured It
Systolic and diastolic blood pressure
To evaluate quercetin supplementation effects on serum lipid and blood pressure responses in overweight patients
Study Type
Randomised, double-blind, placebo-controlled trial
Purpose
To evaluate quercetin supplementation effects on serum lipid and blood pressure responses in overweight patients
Dose
Quercetin supplement
Participants
Overweight patients
Duration
Study period
Results
Quercetin supplementation affected blood pressure and lipid responses, with variation by genetic factors (apolipoprotein E genotype).
How They Measured It
Blood pressure, serum lipids, apolipoprotein E genotype
Metabolic Health
To evaluate effects of quercetin supplementation on cardiometabolic outcomes
Study Type
Umbrella review of meta-analyses
Purpose
To evaluate effects of quercetin supplementation on cardiometabolic outcomes
Dose
Quercetin (various doses)
Participants
Meta-analysis of multiple RCTs
Duration
Various
Results
Quercetin significantly reduced systolic blood pressure and insulin levels. Limited effects on diastolic BP, lipid profile, inflammation markers, and fasting glucose.
How They Measured It
Blood pressure, lipids, glucose, inflammation markers
Athletic Performance & Recovery
To evaluate the effects of quercetin ingestion on neuromuscular function after resistance exercise.
Study Type
Randomized, Double-Blind, Placebo-Controlled
Purpose
To evaluate the effects of quercetin ingestion on neuromuscular function after resistance exercise.
Dose
500 mg quercetin daily
Participants
Trained adults performing resistance exercise
Duration
4 weeks
Results
Quercetin supplementation significantly improved neuromuscular recovery and reduced exercise-induced muscle damage following resistance exercise.
How They Measured It
Muscle strength, EMG activity, perceived exertion, recovery markers
Frequently Asked Questions
Common questions about Quercetin research
There are currently 9 peer-reviewed studies on Quercetin (Quercetin), involving 209 total participants. Research covers Inflammation reduction, Cardiovascular health, Blood pressure reduction and 2 more areas. The overall evidence strength is rated as Strong.
The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (4 human studies), and reported outcomes.
Quercetin has been researched for: Inflammation reduction, Cardiovascular health, Blood pressure reduction, Antioxidant capacity, Post-myocardial infarction recovery. Each area has its own body of evidence which you can explore in the study breakdowns above.
Yes, 4 out of 9 studies are human trials. Human trials carry more weight in our evidence scoring system.
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