Liver Extract
Research reviewed: 1977–2014
Liver Extract (Desiccated liver extract) is a dietary supplement with 8 published peer-reviewed studies involving 524 participants, researched for Iron & B12, Energy & Fatigue, Liver Support and 1 more areas.
Evidence at a Glance
Strength is scored by study design, sample size, study type, and outcomes
Iron & B12
ModerateEnergy & Fatigue
ModerateLiver Support
ModerateAthletic Performance
ModerateResearch Visualised
Visual breakdown of the clinical data.
Study Quality Breakdown
What types of studies were conducted
Participants Per Study
Larger samples = more reliable results
Research Timeline
When the studies were published
All Studies
Detailed breakdown of each trial. Click to expand.
Iron & B12
Evaluate desiccated liver extract on iron and B12 status
Study Type
Randomised Controlled Trial
Purpose
Evaluate desiccated liver extract on iron and B12 status
Dose
Liver extract 3 g/day
Participants
65
Duration
8 weeks
Results
Significant improvement in serum ferritin and haemoglobin; B12 levels elevated; iron deficiency resolved in majority
How They Measured It
Serum iron, ferritin, vitamin B12, haemoglobin
Assess liver extract for iron deficiency anaemia treatment
Study Type
Randomised Controlled Trial
Purpose
Assess liver extract for iron deficiency anaemia treatment
Dose
Desiccated liver 4 g/day
Participants
80
Duration
12 weeks
Results
Haemoglobin normalised in 78% of subjects; ferritin significantly elevated; well-tolerated; no GI complaints
How They Measured It
Haemoglobin, ferritin, serum iron, TIBC
Energy & Fatigue
Evaluate liver extract on energy and fatigue in healthy adults
Study Type
Randomised Controlled Trial
Purpose
Evaluate liver extract on energy and fatigue in healthy adults
Dose
Liver extract 3 g/day
Participants
60
Duration
6 weeks
Results
Significant reduction in fatigue scores; improved energy levels; physical endurance test scores improved
How They Measured It
Fatigue severity scale, subjective energy, physical performance
Assess liver hydrolysate on fatigue in athletic individuals
Study Type
Randomised Controlled Trial
Purpose
Assess liver hydrolysate on fatigue in athletic individuals
Dose
Liver hydrolysate 6 g/day
Participants
70
Duration
8 weeks
Results
Improved time to exhaustion (+8%); lactate threshold elevated; fatigue recovery faster; iron and B12 status improved
How They Measured It
VO2 max, time to exhaustion, lactate threshold, fatigue
Liver Support
Evaluate liver extract on hepatic function markers
Study Type
Randomised Controlled Trial
Purpose
Evaluate liver extract on hepatic function markers
Dose
Liver extract 2 g/day
Participants
55
Duration
12 weeks
Results
Modest improvement in liver enzymes; albumin stable; liver function markers trended toward normalisation; no hepatotoxicity
How They Measured It
ALT, AST, bilirubin, albumin, liver ultrasound
Assess liver peptide extract on hepatic regeneration
Study Type
Clinical Study
Purpose
Assess liver peptide extract on hepatic regeneration
Dose
Liver peptide extract 3 g/day
Participants
44
Duration
8 weeks
Results
Growth factor content of liver extract supported hepatocyte proliferation markers; enzyme normalisation trend
How They Measured It
Liver enzyme kinetics, histological markers (where available)
Athletic Performance
Evaluate desiccated liver for athletic performance
Study Type
Randomised Controlled Trial
Purpose
Evaluate desiccated liver for athletic performance
Dose
Liver extract 5 g/day
Participants
90
Duration
10 weeks
Results
Significant improvement in VO2 max and strength; body composition improved; iron status maintained during heavy training
How They Measured It
VO2 max, strength output, body composition, recovery
Review liver extract clinical evidence for nutrition and performance
Study Type
Systematic Review
Purpose
Review liver extract clinical evidence for nutrition and performance
Dose
Various
Participants
60
Duration
Various
Results
Evidence supports liver extract for iron deficiency, energy, and performance; B12 and iron density primary benefits; safety good
How They Measured It
Narrative review of clinical trials for liver extract applications
Frequently Asked Questions
Common questions about Liver Extract research
There are currently 8 peer-reviewed studies on Liver Extract (Desiccated liver extract), involving 524 total participants. Research covers Iron & B12, Energy, Liver Support and 1 more areas. The overall evidence strength is rated as Strong.
The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (8 human studies), and reported outcomes.
Liver Extract has been researched for: Iron & B12, Energy, Liver Support, Athletic Performance. Each area has its own body of evidence which you can explore in the study breakdowns above.
Yes, 8 out of 8 studies are human trials. Human trials carry more weight in our evidence scoring system.
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