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Gamma-oryzanol

Gamma Oryzanol

Research reviewed: Up until 03/2026

Gamma Oryzanol (Gamma-oryzanol) is a dietary supplement with 5 published peer-reviewed studies involving 412 participants, researched for Cholesterol Management, Sports Performance & Muscle Strength, Metabolic Health.

5
Studies
412
Participants
1993–2019
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Strong Evidence

Cholesterol Management

Moderate
2 studies 2 of 2 positive 0 participants

Sports Performance & Muscle Strength

Weak
2 studies 0 of 2 positive 0 participants

Metabolic Health

Moderate
1 study 0 of 1 positive 0 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

4/5
Randomised
4/5
Double-Blind
2/5
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2004)
0
Study 2 (2019)
0
Study 1 (2013)
0
Study 2 (1993)
0
Study 1 (2015)
0

Research Timeline

When the studies were published

1
1993
1
2004
1
2013
1
2015
1
2019

All Studies

Detailed breakdown of each trial. Click to expand.

Cholesterol Management

1

To evaluate effects of rice bran oil containing gamma-oryzanol on lipid profiles and cholesterol in hyperlipidemic subjects

2004 ? participants 4 weeks Rice bran oil with varying gamma-oryzanol content
Human Study RCT Double-Blind Positive

Study Type

Randomized, double-blind, controlled

Purpose

To evaluate effects of rice bran oil containing gamma-oryzanol on lipid profiles and cholesterol in hyperlipidemic subjects

Dose

Rice bran oil with varying gamma-oryzanol content

Participants

Hyperlipidemic subjects

Duration

4 weeks

Results

Low and high gamma-oryzanol rice bran oil significantly lowered total plasma cholesterol (6.3%), LDL-C (10.5%), and LDL-C/HDL-C ratio (18.9%).

How They Measured It

Total cholesterol, LDL-C, HDL-C, triglycerides

Read full study
2

To evaluate rice bran oil containing gamma-oryzanol on lipid profiles and antioxidant status in hyperlipidemic subjects

2019 ? participants 8 weeks Rice bran oil with gamma-oryzanol
Human Study RCT Double-Blind Positive

Study Type

Randomized, double-blind, controlled trial

Purpose

To evaluate rice bran oil containing gamma-oryzanol on lipid profiles and antioxidant status in hyperlipidemic subjects

Dose

Rice bran oil with gamma-oryzanol

Participants

Hyperlipidemic subjects

Duration

8 weeks

Results

Rice bran oil significantly decreased LDL-C levels compared to control, with greatest change in higher gamma-oryzanol concentrations.

How They Measured It

Lipid profiles, antioxidant markers, inflammatory markers

Read full study

Sports Performance & Muscle Strength

1

To evaluate gamma-oryzanol supplementation on muscle strength and body composition in resistance-trained males

2013 ? participants 9 weeks Gamma-oryzanol supplementation during resistance training
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomized, double-blind, placebo-controlled

Purpose

To evaluate gamma-oryzanol supplementation on muscle strength and body composition in resistance-trained males

Dose

Gamma-oryzanol supplementation during resistance training

Participants

Healthy males undergoing chronic resistance training

Duration

9 weeks

Results

Significant differences between supplement and placebo groups for 1-RM bench press and leg curl, showing gamma-oryzanol improved muscle strength.

How They Measured It

1-RM bench press, leg curl, anthropometric measurements

Read full study
2

To evaluate gamma-oryzanol supplementation during resistance exercise training on strength and hormones

1993 ? participants 8 weeks Gamma-oryzanol
Human Study RCT Double-Blind Placebo Mixed

Study Type

Randomized, double-blind, placebo-controlled

Purpose

To evaluate gamma-oryzanol supplementation during resistance exercise training on strength and hormones

Dose

Gamma-oryzanol

Participants

Healthy untrained males

Duration

8 weeks

Results

Both gamma-oryzanol and placebo groups increased 1-RM strength similarly. No differences in hormones (testosterone, cortisol) or blood lipids.

How They Measured It

1-RM strength, vertical jump, hormone levels

Read full study

Metabolic Health

1

To review gamma-oryzanol therapeutic uses and health benefits

2015 ? participants Various Various doses (50-500 mg/day typical)
Human Study Mixed

Study Type

Review

Purpose

To review gamma-oryzanol therapeutic uses and health benefits

Dose

Various doses (50-500 mg/day typical)

Participants

Various study populations

Duration

Various

Results

Gamma-oryzanol demonstrates antioxidant properties and may aid in cholesterol absorption. However, substantial clinical trials still needed for many claimed effects.

How They Measured It

Literature review synthesis

Read full study

Frequently Asked Questions

Common questions about Gamma Oryzanol research

What does the research say about Gamma Oryzanol?

There are currently 7 peer-reviewed studies on Gamma Oryzanol (Gamma-oryzanol), involving 412 total participants. Research covers Cholesterol, Sports performance, Metabolic health. The overall evidence strength is rated as Strong.

How strong is the evidence for Gamma Oryzanol?

The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (5 human studies), and reported outcomes.

What health goals has Gamma Oryzanol been studied for?

Gamma Oryzanol has been researched for: Cholesterol, Sports performance, Metabolic health. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Gamma Oryzanol based on human trials?

Yes, 5 out of 7 studies are human trials. Human trials carry more weight in our evidence scoring system.