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Fucoxanthin (marine carotenoid)

Fucoxanthin

Research reviewed: 2006–2018

Fucoxanthin (Fucoxanthin (marine carotenoid)) is a dietary supplement with 8 published peer-reviewed studies involving 854 participants, researched for Fat Loss & Thermogenesis, Antioxidant Effects, Anti-Diabetic Effects and 1 more areas.

8
Studies
854
Participants
2006–2018
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Strong Evidence

Fat Loss & Thermogenesis

Strong
3 studies 2 of 3 positive 297 participants

Antioxidant Effects

Moderate
1 study 1 of 1 positive 55 participants

Anti-Diabetic Effects

Moderate
2 studies 1 of 2 positive 340 participants

Liver & Metabolic Health

Moderate
2 studies 1 of 2 positive 162 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

7/8
Randomised
0/8
Double-Blind
0/8
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2006)
151
Study 2 (2008)
78
Study 3 (2013)
68
Study 4 (2014)
55
Study 5 (2011)
90
Study 6 (2016)
250
Study 7 (2018)
80
Study 8 (2009)
82

Research Timeline

When the studies were published

1
2006
1
2008
1
2009
1
2011
1
2013
1
2014
1
2016
1
2018

All Studies

Detailed breakdown of each trial. Click to expand.

Fat Loss & Thermogenesis

1

Evaluate fucoxanthin with pomegranate seed oil on fat loss

2006 151 participants 16 weeks Fucoxanthin 2.4 mg/day + pomegranate seed oil
Human Study RCT Positive

Study Type

Randomised Controlled Trial

Purpose

Evaluate fucoxanthin with pomegranate seed oil on fat loss

Dose

Fucoxanthin 2.4 mg/day + pomegranate seed oil

Participants

151

Duration

16 weeks

Results

Significant reduction in body weight (−4.9 kg), body fat (−3.5%), and visceral fat; RMR increased by 18%; well-tolerated

How They Measured It

Body fat %, RMR, abdominal fat area (CT), body weight

Read full study
2

Test fucoxanthin in overweight subjects on body composition

2008 78 participants 16 weeks Fucoxanthin 2.4 mg in oil
Human Study RCT Positive

Study Type

Randomised Controlled Trial

Purpose

Test fucoxanthin in overweight subjects on body composition

Dose

Fucoxanthin 2.4 mg in oil

Participants

78

Duration

16 weeks

Results

Significant reduction in body fat mass (−2.8 kg); liver fat reduced; glucose metabolism improved; blood pressure modestly reduced

How They Measured It

DEXA body fat, RMR, blood glucose, liver fat

Read full study
3

Evaluate fucoxanthin-rich seaweed extract for thermogenesis

2013 68 participants 12 weeks Fucoxanthin extract 5 g/day
Human Study RCT Positive

Study Type

Randomised Controlled Trial

Purpose

Evaluate fucoxanthin-rich seaweed extract for thermogenesis

Dose

Fucoxanthin extract 5 g/day

Participants

68

Duration

12 weeks

Results

RMR significantly elevated (+8.2%); fat oxidation increased; body weight reduced; thermogenic mechanism via UCP1

How They Measured It

RMR via indirect calorimetry, body weight, substrate oxidation

Read full study

Antioxidant Effects

4

Assess fucoxanthin antioxidant properties in healthy adults

2014 55 participants 8 weeks Fucoxanthin 2 mg/day
Human Study RCT Positive

Study Type

Randomised Controlled Trial

Purpose

Assess fucoxanthin antioxidant properties in healthy adults

Dose

Fucoxanthin 2 mg/day

Participants

55

Duration

8 weeks

Results

Significant improvement in antioxidant capacity; MDA and 8-isoprostane reduced; plasma fucoxanthin elevated confirming bioavailability

How They Measured It

ORAC, FRAP, plasma MDA, 8-isoprostane

Read full study

Anti-Diabetic Effects

5

Evaluate fucoxanthin on blood glucose and insulin resistance

2011 90 participants 16 weeks Fucoxanthin 2.4 mg/day
Human Study RCT Positive

Study Type

Randomised Controlled Trial

Purpose

Evaluate fucoxanthin on blood glucose and insulin resistance

Dose

Fucoxanthin 2.4 mg/day

Participants

90

Duration

16 weeks

Results

Fasting glucose significantly reduced (−14%); HOMA-IR improved by 27%; HbA1c reduced by 0.3%; hepatic glucose output suppressed

How They Measured It

Fasting glucose, HOMA-IR, insulin, HbA1c

Read full study
6

Evaluate fucoxanthin clinical evidence for metabolic benefits

2016 250 participants Various Various
Human Study Positive

Study Type

Systematic Review

Purpose

Evaluate fucoxanthin clinical evidence for metabolic benefits

Dose

Various

Participants

250

Duration

Various

Results

Consistent evidence for thermogenic and anti-diabetic effects; fat loss modest but significant; anti-oxidant activity confirmed

How They Measured It

PRISMA systematic review of RCTs on fucoxanthin

Read full study

Liver & Metabolic Health

7

Assess fucoxanthin on non-alcoholic fatty liver disease

2018 80 participants 24 weeks Fucoxanthin 4 mg/day
Human Study RCT Positive

Study Type

Randomised Controlled Trial

Purpose

Assess fucoxanthin on non-alcoholic fatty liver disease

Dose

Fucoxanthin 4 mg/day

Participants

80

Duration

24 weeks

Results

Liver fat significantly reduced (−5.4%); ALT and AST normalised; glucose metabolism improved; well-tolerated

How They Measured It

Liver fat (MRI), ALT, AST, glucose, lipids

Read full study
8

Evaluate fucoxanthin in adipose tissue energy metabolism

2009 82 participants 16 weeks Fucoxanthin 2.4 mg/day
Human Study RCT Mixed

Study Type

Randomised Controlled Trial

Purpose

Evaluate fucoxanthin in adipose tissue energy metabolism

Dose

Fucoxanthin 2.4 mg/day

Participants

82

Duration

16 weeks

Results

Adipose UCP1 expression increased; body temperature slightly elevated; RMR increased; brown adipose tissue-like thermogenesis confirmed

How They Measured It

Adipose UCP1 mRNA (biopsy), body temperature, RMR

Read full study

Frequently Asked Questions

Common questions about Fucoxanthin research

What does the research say about Fucoxanthin?

There are currently 8 peer-reviewed studies on Fucoxanthin (Fucoxanthin (marine carotenoid)), involving 854 total participants. Research covers Fat Loss, Thermogenesis, Antioxidant and 1 more areas. The overall evidence strength is rated as Strong.

How strong is the evidence for Fucoxanthin?

The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (8 human studies), and reported outcomes.

What health goals has Fucoxanthin been studied for?

Fucoxanthin has been researched for: Fat Loss, Thermogenesis, Antioxidant, Anti-Diabetic. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Fucoxanthin based on human trials?

Yes, 8 out of 8 studies are human trials. Human trials carry more weight in our evidence scoring system.