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Valeriana officinalis

Valerian Root

Research reviewed: Up until 03/2026

Valerian Root (Valeriana officinalis) is a dietary supplement with 9 published peer-reviewed studies involving 534 participants, researched for Sleep Quality & Insomnia, Anxiety & Stress Reduction, Cognitive Function & General Wellbeing.

9
Studies
534
Participants
1982–2023
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Strong Evidence

Sleep Quality & Insomnia

Strong
5 studies 2 of 5 positive 302 participants 2 human

Anxiety & Stress Reduction

Strong
3 studies 3 of 3 positive 216 participants

Cognitive Function & General Wellbeing

Moderate
1 study 0 of 1 positive 16 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

6/9
Randomised
6/9
Double-Blind
6/9
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2006)
16
Study 2 (2010)
18
Study 3 (2020)
60
Study 4 (2023)
80
Study 5 (1982)
128
Study 1 (2006)
48
Study 2 (2013)
68
Study 3 (2013)
100

Research Timeline

When the studies were published

1
1982
1
2000
2
2006
1
2010
2
2013
1
2020
1
2023

All Studies

Detailed breakdown of each trial. Click to expand.

Sleep Quality & Insomnia

1

To determine whether valerian is effective for improving sleep quality in patients with insomnia.

2006 16 participants Various 300-1,215 mg/day of valerian extract
Review/Other Mixed

Study Type

Systematic review and meta-analysis

Purpose

To determine whether valerian is effective for improving sleep quality in patients with insomnia.

Dose

300-1,215 mg/day of valerian extract

Participants

Meta-analysis of 16 randomised placebo-controlled trials

Duration

Various

Results

Patients taking valerian had an 80% greater chance of reporting improved sleep compared to placebo. However, evidence of publication bias was noted and objective measures showed less consistent effects.

How They Measured It

Sleep quality scales, polysomnography across 16 RCTs

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2

To evaluate the effectiveness of valerian as a meta-analysis of randomised placebo-controlled trials for insomnia treatment.

2010 18 participants Various (1-28 days) 300-900 mg/day valerian extract
Review/Other Positive

Study Type

Systematic review and meta-analysis

Purpose

To evaluate the effectiveness of valerian as a meta-analysis of randomised placebo-controlled trials for insomnia treatment.

Dose

300-900 mg/day valerian extract

Participants

Meta-analysis of 18 randomised placebo-controlled trials (N=1,093)

Duration

Various (1-28 days)

Results

No significant difference in sleep latency was found overall (mean difference 0.70 min, 95% CI -3.44 to 4.83). However, subjective sleep quality showed a trend towards improvement. Valerian appears safer than conventional hypnotics.

How They Measured It

Sleep latency (LT), sleep quality score (SQS), objective and subjective measures

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3

To comprehensively evaluate valerian root's effects on sleep problems and associated disorders across all available RCT evidence.

2020 60 participants Various 100-1,260 mg/day Valeriana officinalis
Review/Other Mixed

Study Type

Systematic review and meta-analysis

Purpose

To comprehensively evaluate valerian root's effects on sleep problems and associated disorders across all available RCT evidence.

Dose

100-1,260 mg/day Valeriana officinalis

Participants

Meta-analysis of 60 studies (N=6,894)

Duration

Various

Results

Valerian could be a safe and effective herb to promote sleep and prevent associated disorders. Single doses reduced anxiety in patients undergoing dental procedures. Long-term use (multiple menstrual cycles) effectively reduced premenstrual anxiety.

How They Measured It

Insomnia severity, sleep quality, sleep latency, sleep duration, anxiety

Read full study
4

To evaluate the efficacy and safety of standardised Valeriana officinalis extract in adult subjects with sleep complaints.

2023 80 participants 8 weeks Proprietary standardised V. officinalis extract (equivalent ...
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate the efficacy and safety of standardised Valeriana officinalis extract in adult subjects with sleep complaints.

Dose

Proprietary standardised V. officinalis extract (equivalent to 500 mg root)

Participants

80 adult subjects with sleep complaints

Duration

8 weeks

Results

Standardised valerian extract significantly improved overall sleep quality (PSQI total score), insomnia severity (ISI), and objective sleep measures (actigraphy) compared to placebo. Valerian was well tolerated with no serious adverse events.

How They Measured It

Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), actigraphy

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5

To assess whether a single dose of aqueous extract of valerian root improves subjective sleep quality in people with sleep difficulties.

1982 128 participants Single night observations 450 mg or 900 mg of aqueous extract of valerian root
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled crossover

Purpose

To assess whether a single dose of aqueous extract of valerian root improves subjective sleep quality in people with sleep difficulties.

Dose

450 mg or 900 mg of aqueous extract of valerian root

Participants

128 subjects (including non-insomniac volunteers)

Duration

Single night observations

Results

Valerian significantly improved subjective sleep quality without producing any side effects. A dose of 450 mg was as effective as 900 mg for improving sleep quality perception.

How They Measured It

Stanford Sleepiness Scale, visual analogue sleep scales, questionnaire on sleep quality

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Anxiety & Stress Reduction

1

To evaluate the anxiolytic effect of valerian extract in patients undergoing dental surgical procedures.

2006 48 participants Single dose acute administration 100 mg single dose of valerian extract 60 min before procedu...
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate the anxiolytic effect of valerian extract in patients undergoing dental surgical procedures.

Dose

100 mg single dose of valerian extract 60 min before procedure

Participants

48 patients undergoing dental extraction

Duration

Single dose acute administration

Results

Valerian significantly reduced pre-operative anxiety scores (STAI-S) compared to placebo. Heart rate was also reduced in the valerian group. No adverse cognitive or psychomotor effects were observed.

How They Measured It

State-Trait Anxiety Inventory (STAI), physiological arousal measures

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2

To evaluate the effects of valerian extract on anxiety and sleep disturbance in menopause.

2013 68 participants 8 weeks 530 mg twice daily of Valerian extract
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate the effects of valerian extract on anxiety and sleep disturbance in menopause.

Dose

530 mg twice daily of Valerian extract

Participants

68 postmenopausal women

Duration

8 weeks

Results

Valerian significantly reduced the severity and frequency of hot flashes and improved sleep quality and anxiety symptoms in postmenopausal women compared to placebo. Valerian may be a safe alternative for managing menopausal symptoms.

How They Measured It

State-Trait Anxiety Inventory (STAI), ISI (Insomnia Severity Index), VAS for hot flashes

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3

To evaluate valerian extract for reducing anxiety in women with premenstrual syndrome (PMS).

2013 100 participants 3 menstrual cycles 1,260 mg/day of valerian extract for 7 days per menstrual cy...
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate valerian extract for reducing anxiety in women with premenstrual syndrome (PMS).

Dose

1,260 mg/day of valerian extract for 7 days per menstrual cycle

Participants

100 women with PMS

Duration

3 menstrual cycles

Results

Valerian significantly reduced premenstrual anxiety and mood-related PMS symptoms over 3 cycles compared to placebo. The effect was strongest on anxiety and irritability symptoms.

How They Measured It

Premenstrual Syndrome Daily Symptom Report, STAI

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Cognitive Function & General Wellbeing

1

To assess the effects of valerian on daytime cognitive performance, including sedation, and ensure there is no next-day hangover from nighttime valerian use.

2000 16 participants Single night administration 600 mg valerian extract before bedtime
Human Study RCT Double-Blind Placebo Mixed

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess the effects of valerian on daytime cognitive performance, including sedation, and ensure there is no next-day hangover from nighttime valerian use.

Dose

600 mg valerian extract before bedtime

Participants

16 healthy volunteers

Duration

Single night administration

Results

Valerian did not impair daytime cognitive function or psychomotor performance the following morning. Unlike benzodiazepines, no 'hangover' effect was observed, suggesting valerian is a safer sleep aid.

How They Measured It

Psychomotor testing (critical flicker fusion frequency, choice reaction time), self-rated alertness

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Frequently Asked Questions

Common questions about Valerian Root research

What does the research say about Valerian Root?

There are currently 9 peer-reviewed studies on Valerian Root (Valeriana officinalis), involving 534 total participants. Research covers Sleep quality, Insomnia, Anxiety and 1 more areas. The overall evidence strength is rated as Strong.

How strong is the evidence for Valerian Root?

The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (6 human studies), and reported outcomes.

What health goals has Valerian Root been studied for?

Valerian Root has been researched for: Sleep quality, Insomnia, Anxiety, Stress & relaxation. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Valerian Root based on human trials?

Yes, 6 out of 9 studies are human trials. Human trials carry more weight in our evidence scoring system.