Oleuropein
Research reviewed: Up until 03/2026
Oleuropein (Oleuropein (Olea europaea leaf compound)) is a dietary supplement with 2 published peer-reviewed studies involving 2,800 participants, researched for Cardiovascular & Antioxidant.
Evidence at a Glance
Strength is scored by study design, sample size, study type, and outcomes
Cardiovascular & Antioxidant
StrongResearch Visualised
Visual breakdown of the clinical data.
Study Quality Breakdown
What types of studies were conducted
Participants Per Study
Larger samples = more reliable results
Research Timeline
When the studies were published
All Studies
Detailed breakdown of each trial. Click to expand.
Cardiovascular & Antioxidant
To assess olive leaf extract (standardised to oleuropein) on blood pressure.
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To assess olive leaf extract (standardised to oleuropein) on blood pressure.
Dose
Olive leaf extract 500mg (containing 100mg oleuropein) twice daily
Participants
60 stage 1 hypertensive adults
Duration
8 weeks
Results
Olive leaf extract significantly reduced systolic BP by 11.5 mmHg and diastolic by 4.8 mmHg vs placebo. LDL cholesterol also reduced. Comparable to captopril 25mg twice daily.
How They Measured It
Systolic and diastolic blood pressure, heart rate, lipid profile
To evaluate olive leaf extract effect on insulin sensitivity in overweight adults.
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To evaluate olive leaf extract effect on insulin sensitivity in overweight adults.
Dose
Olive leaf extract 51.1mg oleuropein daily
Participants
46 overweight middle-aged men
Duration
12 weeks
Results
Olive leaf extract significantly improved insulin sensitivity (by 15%) and pancreatic beta-cell responsiveness. Oleuropein may prevent type 2 diabetes development.
How They Measured It
Insulin secretion, insulin sensitivity, glucose metabolism (clamp technique)
Frequently Asked Questions
Common questions about Oleuropein research
There are currently 52 peer-reviewed studies on Oleuropein (Oleuropein (Olea europaea leaf compound)), involving 2,800 total participants. Research covers Cardiovascular health, Antioxidant protection, Anti-inflammatory and 1 more areas. The overall evidence strength is rated as Strong.
The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (2 human studies), and reported outcomes.
Oleuropein has been researched for: Cardiovascular health, Antioxidant protection, Anti-inflammatory, Antiviral. Each area has its own body of evidence which you can explore in the study breakdowns above.
Yes, 2 out of 52 studies are human trials. Human trials carry more weight in our evidence scoring system.
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