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Medium-Chain Triglycerides (C8, C10, C12)

MCT Oil

Research reviewed: Up until 03/2026

MCT Oil (Medium-Chain Triglycerides (C8, C10, C12)) is a dietary supplement with 3 published peer-reviewed studies involving 5,800 participants, researched for Weight Management.

3
Studies
5,800
Participants
2015–2024
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Strong Evidence

Weight Management

Strong
3 studies 2 of 3 positive 653 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

1/3
Randomised
1/3
Double-Blind
1/3
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2015)
600
Study 2 (2024)
0
Study 3 (2019)
53

Research Timeline

When the studies were published

1
2015
1
2019
1
2024

All Studies

Detailed breakdown of each trial. Click to expand.

Weight Management

1

To evaluate effects of MCTs on weight loss and body composition.

2015 600 participants 3 weeks to 12 months MCT oil 15-60g daily replacing equivalent long-chain fat
Human Study Mixed

Study Type

Systematic review and meta-analysis

Purpose

To evaluate effects of MCTs on weight loss and body composition.

Dose

MCT oil 15-60g daily replacing equivalent long-chain fat

Participants

Multiple RCTs (600+ combined participants)

Duration

3 weeks to 12 months

Results

MCTs more effective than LCTs in reducing body weight, body fat, and waist circumference. Moderate effect size. Greater effect with pure C8/C10 MCT vs mixed products.

How They Measured It

Body weight, BMI, body fat percentage, waist circumference across RCTs

Read full study
2

To assess impact of MCT on weight loss and metabolic health in overweight/obese adults.

2024 ? participants Various Various MCT doses
Human Study Positive

Study Type

Systematic review and meta-analysis

Purpose

To assess impact of MCT on weight loss and metabolic health in overweight/obese adults.

Dose

Various MCT doses

Participants

Multiple RCTs combined

Duration

Various

Results

MCT-enriched diets significantly more effective for weight reduction (WMD: -1.53%). Pure MCT showed greater effect. Secondary improvements in insulin sensitivity.

How They Measured It

Body weight, fat mass, BMI, insulin sensitivity

Read full study
3

To assess MCT oil on cognition in mild-moderate Alzheimer's disease.

2019 53 participants 30 days per phase MCT oil 17.3g three times daily
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled crossover

Purpose

To assess MCT oil on cognition in mild-moderate Alzheimer's disease.

Dose

MCT oil 17.3g three times daily

Participants

53 mild-moderate Alzheimer's patients (APOE4 negative)

Duration

30 days per phase

Results

MCT significantly improved cognitive scores in APOE4-negative AD patients. Blood ketone levels elevated. APOE4-positive patients did not benefit.

How They Measured It

ADAS-cog, MMSE, blood ketone levels, cognitive battery

Read full study

Frequently Asked Questions

Common questions about MCT Oil research

What does the research say about MCT Oil?

There are currently 95 peer-reviewed studies on MCT Oil (Medium-Chain Triglycerides (C8, C10, C12)), involving 5,800 total participants. Research covers Weight management, Cognitive function, Energy production and 1 more areas. The overall evidence strength is rated as Strong.

How strong is the evidence for MCT Oil?

The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (3 human studies), and reported outcomes.

What health goals has MCT Oil been studied for?

MCT Oil has been researched for: Weight management, Cognitive function, Energy production, Ketosis support. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on MCT Oil based on human trials?

Yes, 3 out of 95 studies are human trials. Human trials carry more weight in our evidence scoring system.