Irvingia Gabonensis (African Mango)
Research reviewed: 2009–2017
Irvingia Gabonensis (African Mango) (Irvingia gabonensis) is a dietary supplement with 8 published peer-reviewed studies involving 404 participants, researched for Weight Loss, Cholesterol Management, Blood Glucose Control and 1 more areas.
Evidence at a Glance
Strength is scored by study design, sample size, study type, and outcomes
Weight Loss
ModerateCholesterol Management
ModerateBlood Glucose Control
ModerateAdipokine Regulation
ModerateResearch Visualised
Visual breakdown of the clinical data.
Study Quality Breakdown
What types of studies were conducted
Participants Per Study
Larger samples = more reliable results
Research Timeline
When the studies were published
All Studies
Detailed breakdown of each trial. Click to expand.
Weight Loss
Evaluate Irvingia gabonensis seed extract on body weight in obese adults
Study Type
Randomised Double-Blind Placebo-Controlled Trial
Purpose
Evaluate Irvingia gabonensis seed extract on body weight in obese adults
Dose
150 mg twice daily (IGOB131)
Participants
102
Duration
10 weeks
Results
Irvingia group lost 12.8 kg vs 0.7 kg placebo; waist circumference reduced by 16.2 cm; highly significant
How They Measured It
Body weight, BMI, waist circumference, body fat %
Test Irvingia seed extract for obesity management
Study Type
Randomised Controlled Trial
Purpose
Test Irvingia seed extract for obesity management
Dose
300 mg/day
Participants
72
Duration
8 weeks
Results
Significant weight reduction (−5.3 kg) vs placebo (−1.2 kg); improvements in lipid and glucose profiles
How They Measured It
Weight, BMI, body fat via BIA, metabolic markers
Cholesterol Management
Assess Irvingia gabonensis effect on blood lipid profiles
Study Type
Randomised Controlled Trial
Purpose
Assess Irvingia gabonensis effect on blood lipid profiles
Dose
150 mg twice daily
Participants
68
Duration
10 weeks
Results
Total cholesterol reduced by 26%; LDL reduced by 27%; HDL increased by 46%; triglycerides reduced by 25%
How They Measured It
Total cholesterol, LDL, HDL, triglycerides
Review Irvingia gabonensis pharmacological activities and clinical evidence
Study Type
Review Article
Purpose
Review Irvingia gabonensis pharmacological activities and clinical evidence
Dose
N/A
Participants
0
Duration
N/A
Results
Mechanisms include PPAR-gamma inhibition, adipogenesis suppression, fibre-mediated fat malabsorption, and leptin sensitisation
How They Measured It
Narrative review of human and animal studies
Blood Glucose Control
Evaluate Irvingia gabonensis on fasting glucose and insulin resistance
Study Type
Randomised Controlled Trial
Purpose
Evaluate Irvingia gabonensis on fasting glucose and insulin resistance
Dose
300 mg/day
Participants
60
Duration
12 weeks
Results
Fasting glucose reduced by 22%; HOMA-IR improved by 31%; insulin sensitivity significantly enhanced
How They Measured It
Fasting glucose, insulin, HOMA-IR
Investigate Irvingia effect on adipocyte differentiation
Study Type
In Vitro / Mechanistic Study
Purpose
Investigate Irvingia effect on adipocyte differentiation
Dose
Various concentrations
Participants
0
Duration
N/A
Results
Irvingia extract inhibited adipocyte differentiation by 60–80%; suppressed PPAR-gamma and C/EBP-alpha expression
How They Measured It
Cell culture adipogenesis assay, PPAR-gamma expression
Adipokine Regulation
Assess Irvingia gabonensis on leptin and adiponectin levels
Study Type
Randomised Controlled Trial
Purpose
Assess Irvingia gabonensis on leptin and adiponectin levels
Dose
150 mg twice daily
Participants
102
Duration
10 weeks
Results
Adiponectin increased by 160%; leptin reduced by 52%; CRP reduced by 52%; adipokine normalisation correlates with weight loss
How They Measured It
Plasma leptin, adiponectin, CRP, body composition
Explain fibre-based mechanisms of Irvingia for obesity management
Study Type
Mechanistic Review
Purpose
Explain fibre-based mechanisms of Irvingia for obesity management
Dose
N/A
Participants
0
Duration
N/A
Results
High soluble fibre content increases viscosity, slows gastric emptying, reduces energy intake via satiety hormones; prebiotic effects proposed
How They Measured It
Review of viscous fibre, gut microbiome, and satiety mechanisms
Frequently Asked Questions
Common questions about Irvingia Gabonensis (African Mango) research
There are currently 8 peer-reviewed studies on Irvingia Gabonensis (African Mango) (Irvingia gabonensis), involving 404 total participants. Research covers Weight Loss, Cholesterol Management, Blood Glucose Control and 1 more areas. The overall evidence strength is rated as Moderate.
The evidence is currently rated as "Moderate Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (8 human studies), and reported outcomes.
Irvingia Gabonensis (African Mango) has been researched for: Weight Loss, Cholesterol Management, Blood Glucose Control, Adipokine Regulation. Each area has its own body of evidence which you can explore in the study breakdowns above.
Yes, 8 out of 8 studies are human trials. Human trials carry more weight in our evidence scoring system.
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