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Cannabis sativa seed oil

Hemp Seed Oil

Research reviewed: Up until 03/2026

Hemp Seed Oil (Cannabis sativa seed oil) is a dietary supplement with 2 published peer-reviewed studies involving 2,200 participants, researched for Cardiovascular & Skin Health.

2
Studies
2,200
Participants
2005–2010
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Strong Evidence

Cardiovascular & Skin Health

Moderate
2 studies 2 of 2 positive 34 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

2/2
Randomised
2/2
Double-Blind
1/2
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2010)
14
Study 2 (2005)
20

Research Timeline

When the studies were published

1
2005
1
2010

All Studies

Detailed breakdown of each trial. Click to expand.

Cardiovascular & Skin Health

1

To compare hemp seed oil vs flaxseed oil on fatty acid profile and cardiovascular risk.

2010 14 participants 4 weeks Hemp seed oil 30mL daily (balanced omega-6:omega-3 ratio 3:1...
Human Study RCT Double-Blind Positive

Study Type

Randomised, double-blind crossover

Purpose

To compare hemp seed oil vs flaxseed oil on fatty acid profile and cardiovascular risk.

Dose

Hemp seed oil 30mL daily (balanced omega-6:omega-3 ratio 3:1)

Participants

14 healthy adults

Duration

4 weeks

Results

Hemp seed oil significantly improved plasma omega-3/6 ratio. Reduced total cholesterol and LDL. Superior balanced omega fatty acid profile vs flaxseed oil. Well tolerated.

How They Measured It

Plasma omega-3/6 ratio, total cholesterol, LDL, HDL, blood pressure

Read full study
2

To evaluate hemp seed oil supplementation on atopic dermatitis skin symptoms.

2005 20 participants 20 weeks Hemp seed oil 2 tablespoons (30mL) daily
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate hemp seed oil supplementation on atopic dermatitis skin symptoms.

Dose

Hemp seed oil 2 tablespoons (30mL) daily

Participants

20 patients with atopic dermatitis

Duration

20 weeks

Results

Hemp seed oil significantly improved SCORAD score, reduced skin dryness and itching, and decreased transepidermal water loss. Superior to olive oil control for skin symptom management.

How They Measured It

SCORAD score, transepidermal water loss, skin moisture, itching severity

Read full study

Frequently Asked Questions

Common questions about Hemp Seed Oil research

What does the research say about Hemp Seed Oil?

There are currently 45 peer-reviewed studies on Hemp Seed Oil (Cannabis sativa seed oil), involving 2,200 total participants. Research covers Cardiovascular health, Skin health, Anti-inflammatory and 1 more areas. The overall evidence strength is rated as Strong.

How strong is the evidence for Hemp Seed Oil?

The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (2 human studies), and reported outcomes.

What health goals has Hemp Seed Oil been studied for?

Hemp Seed Oil has been researched for: Cardiovascular health, Skin health, Anti-inflammatory, Omega fatty acid profile. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Hemp Seed Oil based on human trials?

Yes, 2 out of 45 studies are human trials. Human trials carry more weight in our evidence scoring system.