Grains of Paradise
Research reviewed: Up until 03/2026
Grains of Paradise (Aframomum melegueta) is a dietary supplement with 3 published peer-reviewed studies involving 198 participants, researched for Thermogenesis & Energy Expenditure, Fat Loss & Body Composition.
Evidence at a Glance
Strength is scored by study design, sample size, study type, and outcomes
Thermogenesis & Energy Expenditure
ModerateFat Loss & Body Composition
ModerateResearch Visualised
Visual breakdown of the clinical data.
Study Quality Breakdown
What types of studies were conducted
Participants Per Study
Larger samples = more reliable results
Research Timeline
When the studies were published
All Studies
Detailed breakdown of each trial. Click to expand.
Thermogenesis & Energy Expenditure
To evaluate effects of Grains of Paradise extract on whole-body energy expenditure and visceral fat in humans
Study Type
Single-blind, randomized, placebo-controlled crossover
Purpose
To evaluate effects of Grains of Paradise extract on whole-body energy expenditure and visceral fat in humans
Dose
40 mg Grains of Paradise extract/day
Participants
Healthy male volunteers (aged 20-32)
Duration
4 weeks
Results
Daily ingestion of Grains of Paradise extract increased whole-body energy expenditure and decreased visceral fat in humans.
How They Measured It
Whole-body energy expenditure via indirect calorimetry, visceral fat
To evaluate prolonged treatment with Grains of Paradise extract on thermogenesis and body fat in humans with low brown fat activity
Study Type
Single-blind, randomized, placebo-controlled
Purpose
To evaluate prolonged treatment with Grains of Paradise extract on thermogenesis and body fat in humans with low brown fat activity
Dose
40 mg Grains of Paradise extract/day
Participants
Healthy young males with reduced BAT
Duration
5 weeks
Results
Prolonged Grains of Paradise treatment recruits adaptive thermogenesis and reduces body fat in humans with low brown fat activity.
How They Measured It
Brown adipose tissue activity, body composition, thermogenesis
Fat Loss & Body Composition
To evaluate Aframomum melegueta seed extract (6-paradol standardized) on visceral fat and energy expenditure in overweight adults
Study Type
Randomized, double-blind, placebo-controlled
Purpose
To evaluate Aframomum melegueta seed extract (6-paradol standardized) on visceral fat and energy expenditure in overweight adults
Dose
250 mg Aframomum melegueta seed extract twice daily
Participants
70 overweight male and female subjects (BMI 25-30)
Duration
12 weeks
Results
Energy expenditure in extract group showed 18.55% increase compared to placebo. Significant improvements in body composition.
How They Measured It
Energy expenditure, visceral fat, body composition via DEXA
Frequently Asked Questions
Common questions about Grains of Paradise research
There are currently 4 peer-reviewed studies on Grains of Paradise (Aframomum melegueta), involving 198 total participants. Research covers Thermogenesis, Fat burning, Metabolic health. The overall evidence strength is rated as Strong.
The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (3 human studies), and reported outcomes.
Grains of Paradise has been researched for: Thermogenesis, Fat burning, Metabolic health. Each area has its own body of evidence which you can explore in the study breakdowns above.
Yes, 3 out of 4 studies are human trials. Human trials carry more weight in our evidence scoring system.
