Ginger Extract
Research reviewed: Up until 03/2026
Ginger Extract (Zingiber officinale (Ginger Root)) is a dietary supplement with 10 published peer-reviewed studies involving 3,397 participants, researched for Blood Pressure & Cholesterol, Anti-inflammatory & Metabolic Effects, Clinical trials.
Evidence at a Glance
Strength is scored by study design, sample size, study type, and outcomes
Blood Pressure & Cholesterol
ModerateAnti-inflammatory & Metabolic Effects
StrongClinical trials
ModerateResearch Visualised
Visual breakdown of the clinical data.
Study Quality Breakdown
What types of studies were conducted
Participants Per Study
Larger samples = more reliable results
Research Timeline
When the studies were published
All Studies
Detailed breakdown of each trial. Click to expand.
Blood Pressure & Cholesterol
To evaluate ginger (Zingiber officinale) supplementation on biomarkers of cardiovascular disease.
Study Type
Systematic review of randomised controlled trials
Purpose
To evaluate ginger (Zingiber officinale) supplementation on biomarkers of cardiovascular disease.
Dose
Various ginger doses (0.5β5 g/day)
Participants
Multiple RCTs (published up to January 2025)
Duration
4β16 weeks
Results
Ginger supplementation significantly reduced SBP, TC, LDL-C, and TG in pooled analyses. CRP and fasting glucose were also improved in subgroups. Effect sizes were moderate and consistent across different ginger formulations (powder, extract, fresh).
How They Measured It
Pooled blood pressure, lipid panel, CRP, fasting glucose from RCTs
To meta-analyse the effect of ginger supplementation on lipid profile in humans.
Study Type
Systematic review and meta-analysis
Purpose
To meta-analyse the effect of ginger supplementation on lipid profile in humans.
Dose
Various ginger doses and forms
Participants
Multiple RCTs (>1,000 participants)
Duration
4β12 weeks
Results
Ginger significantly reduced TC (WMD β9.4 mg/dL), TG (WMD β12.6 mg/dL), and LDL-C. HDL-C showed a non-significant trend toward improvement. Subgroup analysis showed stronger effects in diabetic patients and at doses β₯2 g/day.
How They Measured It
Pooled TC, LDL-C, HDL-C, TG from eligible RCTs (2010β2022)
To analyse the effect of Zingiber officinale on dyslipidaemia, blood pressure, and inflammation as cardiovascular risk factors.
Study Type
Systematic review
Purpose
To analyse the effect of Zingiber officinale on dyslipidaemia, blood pressure, and inflammation as cardiovascular risk factors.
Dose
Various (predominantly 1β3 g/day ginger powder)
Participants
Multiple clinical trials reviewed
Duration
4β16 weeks
Results
Evidence supports a beneficial effect of Zingiber officinale on dyslipidaemia and inflammation. Blood pressure effects were inconsistent but generally trending toward reduction. The review identified gaps in high-quality evidence and recommended further rigorous RCTs.
How They Measured It
Synthesis of lipid endpoints, SBP, DBP, and inflammatory markers from eligible clinical trials
To assess ginger powder supplementation on blood pressure and lipid profile in patients with coronary artery disease.
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To assess ginger powder supplementation on blood pressure and lipid profile in patients with coronary artery disease.
Dose
4 g/day ginger powder
Participants
85 patients with coronary artery disease
Duration
8 weeks
Results
Ginger powder significantly reduced TC (β12%), LDL-C (β14%), TG (β18%) and blood pressure compared to placebo. HDL-C improved marginally. Platelet aggregation was also reduced. Results support ginger as a complementary supplement in coronary artery disease.
How They Measured It
SBP, DBP, TC, LDL-C, HDL-C, TG at 4 and 8 weeks
Anti-inflammatory & Metabolic Effects
To evaluate ginger supplementation on inflammatory and metabolic markers in type 2 diabetes.
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To evaluate ginger supplementation on inflammatory and metabolic markers in type 2 diabetes.
Dose
2 g/day ginger powder
Participants
88 patients with type 2 diabetes
Duration
12 weeks
Results
Ginger significantly reduced CRP (β30%), TNF-alpha (β24%), and IL-6. HbA1c and fasting glucose improved significantly. Insulin resistance (HOMA-IR) was meaningfully reduced. The combined anti-inflammatory and glycaemic benefits support ginger for cardiovascular risk reduction in diabetes.
How They Measured It
CRP, IL-6, TNF-alpha, HbA1c, fasting glucose, insulin resistance
To assess ginger capsules vs placebo on blood pressure in hypertensive patients.
Study Type
Randomised, double-blind, controlled
Purpose
To assess ginger capsules vs placebo on blood pressure in hypertensive patients.
Dose
3 g/day ginger capsules
Participants
75 hypertensive adults
Duration
8 weeks
Results
Ginger supplementation produced significant reductions in SBP (β6.4 mmHg) and DBP (β3.9 mmHg) compared to placebo (p=0.02). Proposed mechanism includes calcium channel antagonism and ACE inhibition by gingerols and shogaols.
How They Measured It
Clinic SBP and DBP, 24-h ambulatory blood pressure
To investigate the effect of ginger extract on oxidative stress and endothelial function markers in obese adults.
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To investigate the effect of ginger extract on oxidative stress and endothelial function markers in obese adults.
Dose
1,600 mg/day ginger extract
Participants
60 obese adults with cardiovascular risk factors
Duration
12 weeks
Results
Ginger extract significantly reduced MDA (oxidative stress marker) and improved FMD (endothelial function). TC and LDL-C were reduced. ICAM-1 (inflammation marker) was significantly lower vs placebo. Results support ginger for endothelial protection in obese cardiovascular risk patients.
How They Measured It
MDA, SOD, FMD, ICAM-1, blood pressure, lipid panel
To evaluate ginger supplementation on blood pressure specifically across controlled clinical trials.
Study Type
Systematic review and meta-analysis
Purpose
To evaluate ginger supplementation on blood pressure specifically across controlled clinical trials.
Dose
Various (0.5β5 g/day)
Participants
Multiple RCTs pooled
Duration
4β16 weeks
Results
Ginger significantly reduced SBP (WMD β6.36 mmHg) and DBP (WMD β2.12 mmHg) overall. Effects were dose-dependent and stronger in hypertensive subjects and at treatment durations β₯8 weeks. Ginger is a promising adjunct for blood pressure management.
How They Measured It
Pooled SBP and DBP changes, subgroup analysis by dose, duration, and hypertension status
To evaluate ginger on lipid profile in patients with non-alcoholic fatty liver disease (NAFLD).
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To evaluate ginger on lipid profile in patients with non-alcoholic fatty liver disease (NAFLD).
Dose
2 g/day ginger powder
Participants
64 adults with NAFLD
Duration
12 weeks
Results
Ginger significantly reduced TC (β12%), TG (β16%), and LDL-C (β10%) vs placebo. Liver enzymes (ALT, AST) and hepatic steatosis on ultrasound also improved. The lipid-lowering effects in NAFLD are particularly relevant given the high cardiovascular risk in this population.
How They Measured It
TC, LDL-C, HDL-C, TG, liver ultrasound, liver enzymes
Clinical trials
To assess the effect of standardized ginger root powder as adjuvant therapy on chemotherapy-induced nausea and vomiting (CINV).
Study Type
Multicenter, double-blind, placebo-controlled randomized trial
Purpose
To assess the effect of standardized ginger root powder as adjuvant therapy on chemotherapy-induced nausea and vomiting (CINV).
Dose
4 standardized ginger capsules/day totaling 84 mg/day active gingerols/shogaols for 5 days per chemotherapy cycle
Participants
103 chemotherapy-naΓ―ve adults (Australia)
Duration
3 chemotherapy cycles
Results
Ginger significantly improved nausea-related QoL (P=0.003), overall CINV-related QoL (P<0.001), and reduced delayed nausea severity (P=0.003). Significantly lower incidence of delayed nausea and vomiting at Cycles 2 and 3. Lower malnutrition rate at Cycle 3.
How They Measured It
Nausea-related QoL, overall CINV-related QoL, delayed nausea/vomiting incidence, fatigue, nutritional status, malnutrition rate
Frequently Asked Questions
Common questions about Ginger Extract research
There are currently 10 peer-reviewed studies on Ginger Extract (Zingiber officinale (Ginger Root)), involving 3,397 total participants. Research covers Blood pressure management, Cholesterol reduction, Anti-inflammatory cardiovascular effects and 1 more areas. The overall evidence strength is rated as Strong.
The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (6 human studies), and reported outcomes.
Ginger Extract has been researched for: Blood pressure management, Cholesterol reduction, Anti-inflammatory cardiovascular effects, Triglyceride lowering. Each area has its own body of evidence which you can explore in the study breakdowns above.
Yes, 6 out of 10 studies are human trials. Human trials carry more weight in our evidence scoring system.
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