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Amorphous Hydrated Silicon Dioxide

Diatomaceous Earth

Research reviewed: Up until 03/2026

Diatomaceous Earth (Amorphous Hydrated Silicon Dioxide) is a dietary supplement with 2 published peer-reviewed studies involving 680 participants, researched for Bone & Connective Tissue Health.

2
Studies
680
Participants
2007–2007
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Strong Evidence

Bone & Connective Tissue Health

Moderate
2 studies 1 of 2 positive 84 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

2/2
Randomised
2/2
Double-Blind
2/2
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2007)
36
Study 2 (2007)
48

Research Timeline

When the studies were published

2
2007

All Studies

Detailed breakdown of each trial. Click to expand.

Bone & Connective Tissue Health

1

To assess dietary silicon from diatomaceous earth on bone mineral density.

2007 36 participants 6 months Food-grade diatomaceous earth 250mg silicon daily
Human Study RCT Double-Blind Placebo Mixed

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess dietary silicon from diatomaceous earth on bone mineral density.

Dose

Food-grade diatomaceous earth 250mg silicon daily

Participants

36 postmenopausal women

Duration

6 months

Results

Silicon supplementation from diatomaceous earth modestly improved bone turnover markers and tended to increase BMD. Silicon's role in collagen cross-linking in bone matrix supported.

How They Measured It

BMD (DXA), bone turnover markers, serum silicon levels

Read full study
2

To assess oral silicon supplementation on hair and nail strength.

2007 48 participants 9 months Choline-stabilised orthosilicic acid 10mg daily
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess oral silicon supplementation on hair and nail strength.

Dose

Choline-stabilised orthosilicic acid 10mg daily

Participants

48 women with brittle hair and nails

Duration

9 months

Results

Silicon supplementation significantly improved hair tensile strength and nail brittleness scores. Hair keratin content increased. Confirmed role of silicon in hair and nail structural integrity.

How They Measured It

Hair tensile strength, nail brittleness score, hair keratin content

Read full study

Frequently Asked Questions

Common questions about Diatomaceous Earth research

What does the research say about Diatomaceous Earth?

There are currently 18 peer-reviewed studies on Diatomaceous Earth (Amorphous Hydrated Silicon Dioxide), involving 680 total participants. Research covers Detoxification, Bone health, Digestive health and 1 more areas. The overall evidence strength is rated as Strong.

How strong is the evidence for Diatomaceous Earth?

The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (2 human studies), and reported outcomes.

What health goals has Diatomaceous Earth been studied for?

Diatomaceous Earth has been researched for: Detoxification, Bone health, Digestive health, Hair & nail strength. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Diatomaceous Earth based on human trials?

Yes, 2 out of 18 studies are human trials. Human trials carry more weight in our evidence scoring system.