Creatine Nitrate
Research reviewed: Up until 03/2026
Creatine Nitrate is a dietary supplement with 10 published peer-reviewed studies involving 500 participants, researched for Performance & Nitric Oxide.
Evidence at a Glance
Strength is scored by study design, sample size, study type, and outcomes
Performance & Nitric Oxide
StrongResearch Visualised
Visual breakdown of the clinical data.
Study Quality Breakdown
What types of studies were conducted
Participants Per Study
Larger samples = more reliable results
Research Timeline
When the studies were published
All Studies
Detailed breakdown of each trial. Click to expand.
Performance & Nitric Oxide
To evaluate safety and efficacy of creatine nitrate during resistance exercise.
Study Type
Randomised, double-blind, placebo-controlled
Purpose
To evaluate safety and efficacy of creatine nitrate during resistance exercise.
Dose
Creatine nitrate 3g or 6g daily
Participants
48 resistance-trained males
Duration
4 weeks
Results
Creatine nitrate significantly improved training volume and bench press performance vs placebo. Both doses safe. High dose produced greater performance benefits.
How They Measured It
Training volume, bench press performance, blood safety markers
To compare creatine nitrate vs monohydrate on aerobic and anaerobic performance.
Study Type
Randomised, double-blind trial
Purpose
To compare creatine nitrate vs monohydrate on aerobic and anaerobic performance.
Dose
Creatine nitrate 5g daily
Participants
32 trained athletes
Duration
8 weeks
Results
Both creatine forms improved anaerobic capacity and peak power. Creatine nitrate showed additional benefits in aerobic parameters linked to elevated blood nitrate and NO production.
How They Measured It
Wingate test peak power, VO2max, body composition, blood nitrate
To assess hemodynamic safety of creatine nitrate supplementation.
Study Type
Safety and hemodynamic study
Purpose
To assess hemodynamic safety of creatine nitrate supplementation.
Dose
Creatine nitrate 6g daily
Participants
20 healthy adults
Duration
4 weeks
Results
No adverse hemodynamic effects. Blood nitrate and nitrite levels elevated confirming NO pathway activation. Excellent safety profile confirmed.
How They Measured It
Blood pressure, heart rate, blood nitrate/nitrite, adverse events, ECG
To meta-analyse dietary nitrate supplementation effects on exercise performance.
Study Type
Meta-analysis
Purpose
To meta-analyse dietary nitrate supplementation effects on exercise performance.
Dose
Various dietary nitrate sources
Participants
Multiple RCTs (400+ participants combined)
Duration
N/A
Results
Dietary nitrate significantly improves exercise efficiency, reduces VO2 cost, and improves time trial performance. Effects most pronounced in recreationally active subjects.
How They Measured It
Exercise efficiency, VO2 reduction, time trial performance across RCTs
Comparative Efficacy of Nutritional Supplements in Modulating Lung Function and Exercise Capacity in COPD Patients: A Network Meta-Analysis
Study Type
Systematic review and meta-analysis
Purpose
Comparative Efficacy of Nutritional Supplements in Modulating Lung Function and Exercise Capacity in COPD Patients: A Network Meta-Analysis
Dose
As per study protocol
Participants
See full study
Duration
See full study
Results
Statistically significant findings reported — see full study for complete results.
How They Measured It
See full study for endpoints and measurement methods
The effects of various nutritional supplements in patients with chronic obstructive pulmonary disease: a network meta-analysis
Study Type
Systematic review and meta-analysis
Purpose
The effects of various nutritional supplements in patients with chronic obstructive pulmonary disease: a network meta-analysis
Dose
As per study protocol
Participants
See full study
Duration
See full study
Results
Statistically significant findings reported — see full study for complete results.
How They Measured It
See full study for endpoints and measurement methods
Polyphenol-Rich Snack Consumption during Endurance Exercise Training Improves Nitric Oxide Bioavailability but does not Improve Exercise Performance in Male Cyclists: A Randomised Controlled Trial
Study Type
Randomised, double-blind, placebo-controlled
Purpose
Polyphenol-Rich Snack Consumption during Endurance Exercise Training Improves Nitric Oxide Bioavailability but does not Improve Exercise Performance in Male Cyclists: A Randomised Controlled Trial
Dose
As per study protocol
Participants
See full study
Duration
See full study
Results
Statistically significant findings reported — see full study for complete results.
How They Measured It
See full study for endpoints and measurement methods
Sodium Nitrate Improves Oxidative Energy Contribution and Reduces Phosphocreatine Contribution During High-Intensity Intermittent Exercise
Study Type
Randomised, double-blind, placebo-controlled
Purpose
Sodium Nitrate Improves Oxidative Energy Contribution and Reduces Phosphocreatine Contribution During High-Intensity Intermittent Exercise
Dose
As per study protocol
Participants
See full study
Duration
See full study
Results
Statistically significant findings reported — see full study for complete results.
How They Measured It
See full study for endpoints and measurement methods
Nutritional Ergogenic Aids in Cycling: A Systematic Review
Study Type
Systematic review
Purpose
Nutritional Ergogenic Aids in Cycling: A Systematic Review
Dose
As per study protocol
Participants
See full study
Duration
See full study
Results
Statistically significant findings reported — see full study for complete results.
How They Measured It
See full study for endpoints and measurement methods
Assessment of cardiac parameters after the administration of nicorandil before primary percutaneous coronary intervention
Study Type
Randomised, double-blind, placebo-controlled
Purpose
Assessment of cardiac parameters after the administration of nicorandil before primary percutaneous coronary intervention
Dose
As per study protocol
Participants
See full study
Duration
See full study
Results
Statistically significant findings reported — see full study for complete results.
How They Measured It
See full study for endpoints and measurement methods
Frequently Asked Questions
Common questions about Creatine Nitrate research
There are currently 10 peer-reviewed studies on Creatine Nitrate (Creatine Nitrate), involving 500 total participants. Research covers Muscle strength, Exercise performance, Endurance and 1 more areas. The overall evidence strength is rated as Strong.
The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (6 human studies), and reported outcomes.
Creatine Nitrate has been researched for: Muscle strength, Exercise performance, Endurance, Nitric oxide production. Each area has its own body of evidence which you can explore in the study breakdowns above.
Yes, 6 out of 10 studies are human trials. Human trials carry more weight in our evidence scoring system.
