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Creatine Nitrate

Creatine Nitrate

Research reviewed: Up until 03/2026

Creatine Nitrate is a dietary supplement with 4 published peer-reviewed studies involving 680 participants, researched for Performance & Nitric Oxide.

4
Studies
680
Participants
2014–2017
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Strong Evidence

Performance & Nitric Oxide

Moderate
4 studies 1 of 4 positive 500 participants

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

2/4
Randomised
2/4
Double-Blind
1/4
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2014)
48
Study 2 (2016)
32
Study 3 (2017)
20
Study 4 (2017)
400

Research Timeline

When the studies were published

1
2014
1
2016
2
2017

All Studies

Detailed breakdown of each trial. Click to expand.

Performance & Nitric Oxide

1

To evaluate safety and efficacy of creatine nitrate during resistance exercise.

2014 48 participants 4 weeks Creatine nitrate 3g or 6g daily
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate safety and efficacy of creatine nitrate during resistance exercise.

Dose

Creatine nitrate 3g or 6g daily

Participants

48 resistance-trained males

Duration

4 weeks

Results

Creatine nitrate significantly improved training volume and bench press performance vs placebo. Both doses safe. High dose produced greater performance benefits.

How They Measured It

Training volume, bench press performance, blood safety markers

Read full study
2

To compare creatine nitrate vs monohydrate on aerobic and anaerobic performance.

2016 32 participants 8 weeks Creatine nitrate 5g daily
Human Study RCT Double-Blind Mixed

Study Type

Randomised, double-blind trial

Purpose

To compare creatine nitrate vs monohydrate on aerobic and anaerobic performance.

Dose

Creatine nitrate 5g daily

Participants

32 trained athletes

Duration

8 weeks

Results

Both creatine forms improved anaerobic capacity and peak power. Creatine nitrate showed additional benefits in aerobic parameters linked to elevated blood nitrate and NO production.

How They Measured It

Wingate test peak power, VO2max, body composition, blood nitrate

Read full study
3

To assess hemodynamic safety of creatine nitrate supplementation.

2017 20 participants 4 weeks Creatine nitrate 6g daily
Human Study Mixed

Study Type

Safety and hemodynamic study

Purpose

To assess hemodynamic safety of creatine nitrate supplementation.

Dose

Creatine nitrate 6g daily

Participants

20 healthy adults

Duration

4 weeks

Results

No adverse hemodynamic effects. Blood nitrate and nitrite levels elevated confirming NO pathway activation. Excellent safety profile confirmed.

How They Measured It

Blood pressure, heart rate, blood nitrate/nitrite, adverse events, ECG

Read full study
4

To meta-analyse dietary nitrate supplementation effects on exercise performance.

2017 400 participants N/A Various dietary nitrate sources
Human Study Positive

Study Type

Meta-analysis

Purpose

To meta-analyse dietary nitrate supplementation effects on exercise performance.

Dose

Various dietary nitrate sources

Participants

Multiple RCTs (400+ participants combined)

Duration

N/A

Results

Dietary nitrate significantly improves exercise efficiency, reduces VO2 cost, and improves time trial performance. Effects most pronounced in recreationally active subjects.

How They Measured It

Exercise efficiency, VO2 reduction, time trial performance across RCTs

Read full study

Frequently Asked Questions

Common questions about Creatine Nitrate research

What does the research say about Creatine Nitrate?

There are currently 14 peer-reviewed studies on Creatine Nitrate (Creatine Nitrate), involving 680 total participants. Research covers Muscle strength, Exercise performance, Endurance and 1 more areas. The overall evidence strength is rated as Strong.

How strong is the evidence for Creatine Nitrate?

The evidence is currently rated as "Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (4 human studies), and reported outcomes.

What health goals has Creatine Nitrate been studied for?

Creatine Nitrate has been researched for: Muscle strength, Exercise performance, Endurance, Nitric oxide production. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Creatine Nitrate based on human trials?

Yes, 4 out of 14 studies are human trials. Human trials carry more weight in our evidence scoring system.