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Boswellia serrata

Boswellia

Research reviewed: Up until 03/2026

Boswellia (Boswellia serrata) is a dietary supplement with 18 published peer-reviewed studies involving 700 participants, researched for Joint Health & Osteoarthritis, Inflammation, Pain Relief.

18
Studies
700
Participants
1998–2026
Research Span

Evidence at a Glance

Strength is scored by study design, sample size, study type, and outcomes

Overall: Very Strong Evidence

Joint Health & Osteoarthritis

Strong
10 studies 9 of 10 positive 220 participants 7 human

Inflammation

Strong
3 studies 2 of 3 positive 205 participants

Pain Relief

Moderate
5 studies 2 of 5 positive 275 participants 4 human

Research Visualised

Visual breakdown of the clinical data.

Study Quality Breakdown

What types of studies were conducted

14/18
Randomised
12/18
Double-Blind
12/18
Placebo-Controlled

Participants Per Study

Larger samples = more reliable results

Study 1 (2003)
30
Study 2 (2024)
128
Study 3 (2025)
62
Study 4 (2020)
0
Study 13 (2025)
0
Study 14 (2026)
0
Study 15 (2025)
0
Study 16 (2025)
0

Research Timeline

When the studies were published

1
1998
1
2001
1
2003
1
2008
1
2010
2
2011
1
2014
1
2018
1
2020
1
2024
6
2025
1
2026

All Studies

Detailed breakdown of each trial. Click to expand.

Joint Health & Osteoarthritis

1

To evaluate Boswellia serrata extract (BSE) efficacy in knee osteoarthritis

2003 30 participants 8 weeks 333 mg BSE three times daily
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate Boswellia serrata extract (BSE) efficacy in knee osteoarthritis

Dose

333 mg BSE three times daily

Participants

30 patients with knee OA

Duration

8 weeks

Results

Significant reduction in knee pain, stiffness, and increased knee flexion vs placebo (p<0.001).

How They Measured It

WOMAC pain scale, VAS, mobility

Read full study
2

To assess the fast-acting efficacy of standardised Boswellia extract in knee OA

2024 128 participants 90 days 100 mg or 250 mg standardised BSE
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess the fast-acting efficacy of standardised Boswellia extract in knee OA

Dose

100 mg or 250 mg standardised BSE

Participants

128 knee OA patients

Duration

90 days

Results

Significant pain and function improvements observed from day 5 onwards in both BSE groups vs placebo.

How They Measured It

WOMAC, patient global impression, knee strength

Read full study
3

To assess Boswellia and Apium graveolens combination on knee OA and cartilage degeneration

2025 62 participants 24 weeks Boswellia 200 mg + Apium extract
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To assess Boswellia and Apium graveolens combination on knee OA and cartilage degeneration

Dose

Boswellia 200 mg + Apium extract

Participants

62 knee OA patients

Duration

24 weeks

Results

Significant improvements in pain, stiffness, and function scores; reduced cartilage degeneration on MRI.

How They Measured It

WOMAC, VAS, MRI cartilage assessment

Read full study
4

To evaluate effectiveness of Boswellia and its extract in osteoarthritis patients

2020 ? participants Various Various
Review/Other Positive

Study Type

Systematic review and meta-analysis

Purpose

To evaluate effectiveness of Boswellia and its extract in osteoarthritis patients

Dose

Various

Participants

Multiple trials pooled

Duration

Various

Results

Boswellia significantly reduced pain and improved function in OA; SMD -0.69 for pain relief (p<0.0001).

How They Measured It

Pain scores, physical function, WOMAC

Read full study
13

Clinical Benefits of Boswellia Serrata (BOSMAX®) in Early Knee Osteoarthritis: A Randomized, Placebo-Controlled, Double-Blind Study

2025 ? participants See full study As per study protocol
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

Clinical Benefits of Boswellia Serrata (BOSMAX®) in Early Knee Osteoarthritis: A Randomized, Placebo-Controlled, Double-Blind Study

Dose

As per study protocol

Participants

See full study

Duration

See full study

Results

Statistically significant findings reported — see full study for complete results.

How They Measured It

See full study for endpoints and measurement methods

Read full study
14

Evaluating the efficacy and safety of Curcuma longa, Boswellia serrata, and their mixed formulation in treating knee osteoarthritis: A systematic review and network meta-analysis

2026 ? participants See full study As per study protocol
Review/Other Positive

Study Type

Systematic review and meta-analysis

Purpose

Evaluating the efficacy and safety of Curcuma longa, Boswellia serrata, and their mixed formulation in treating knee osteoarthritis: A systematic review and network meta-analysis

Dose

As per study protocol

Participants

See full study

Duration

See full study

Results

Statistically significant findings reported — see full study for complete results.

How They Measured It

See full study for endpoints and measurement methods

Read full study
15

Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis

2025 ? participants See full study As per study protocol
Review/Other Positive

Study Type

Systematic review and meta-analysis

Purpose

Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis

Dose

As per study protocol

Participants

See full study

Duration

See full study

Results

Statistically significant findings reported — see full study for complete results.

How They Measured It

See full study for endpoints and measurement methods

Read full study
16

Effect of a combination of C. longa and B. serrata extracts on hand osteoarthritis. Results of a double-blind, randomized, placebo-controlled, multicenter trial

2025 ? participants See full study As per study protocol
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

Effect of a combination of C. longa and B. serrata extracts on hand osteoarthritis. Results of a double-blind, randomized, placebo-controlled, multicenter trial

Dose

As per study protocol

Participants

See full study

Duration

See full study

Results

Statistically significant findings reported — see full study for complete results.

How They Measured It

See full study for endpoints and measurement methods

Read full study
17

The effect of turmeric-Boswellia formulation (Rhuleave-K) in posture-related low back soreness and discomfort: A randomized double blinded placebo controlled trial

2025 ? participants See full study As per study protocol
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

The effect of turmeric-Boswellia formulation (Rhuleave-K) in posture-related low back soreness and discomfort: A randomized double blinded placebo controlled trial

Dose

As per study protocol

Participants

See full study

Duration

See full study

Results

Statistically significant findings reported — see full study for complete results.

How They Measured It

See full study for endpoints and measurement methods

Read full study
18

Randomized controlled trial of bromelain and alpha-lipoic acid in breast conservative surgery

2025 ? participants See full study As per study protocol
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

Randomized controlled trial of bromelain and alpha-lipoic acid in breast conservative surgery

Dose

As per study protocol

Participants

See full study

Duration

See full study

Results

Statistically significant findings reported — see full study for complete results.

How They Measured It

See full study for endpoints and measurement methods

Read full study

Inflammation

5

To investigate anti-inflammatory effects of Boswellic acid in inflammatory bowel disease

2001 44 participants 8 weeks 400 mg Boswellia extract 3x daily
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To investigate anti-inflammatory effects of Boswellic acid in inflammatory bowel disease

Dose

400 mg Boswellia extract 3x daily

Participants

44 Crohn's disease patients

Duration

8 weeks

Results

Boswellia maintained remission in 59% of patients vs 26% placebo; significant reduction in CRP.

How They Measured It

Crohn's Disease Activity Index, CRP, gut biopsy

Read full study
6

To evaluate BSE on inflammatory markers in patients with rheumatoid arthritis

2008 81 participants 16 weeks 1200 mg/day BSE
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate BSE on inflammatory markers in patients with rheumatoid arthritis

Dose

1200 mg/day BSE

Participants

81 RA patients

Duration

16 weeks

Results

Significant reduction in joint tenderness, swelling, and inflammatory markers vs placebo (p<0.001).

How They Measured It

CRP, ESR, joint tenderness and swelling

Read full study
7

To assess anti-inflammatory effects of Boswellia in asthma patients

1998 80 participants 6 weeks 300 mg BSE 3x daily
Human Study RCT Mixed

Study Type

Randomised, controlled

Purpose

To assess anti-inflammatory effects of Boswellia in asthma patients

Dose

300 mg BSE 3x daily

Participants

80 bronchial asthma patients

Duration

6 weeks

Results

70% of BSE group showed improvements in asthma symptoms and lung function vs 27% placebo (p<0.001).

How They Measured It

Lung function tests (FEV1, FVC), asthma symptoms

Read full study

Pain Relief

8

To test Boswellia's efficacy for low back pain in patients with degenerative disc disease

2014 120 participants 6 months 500 mg Boswellia extract twice daily
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To test Boswellia's efficacy for low back pain in patients with degenerative disc disease

Dose

500 mg Boswellia extract twice daily

Participants

120 adults with low back pain

Duration

6 months

Results

Significant pain reduction and functional improvement vs placebo (VAS -42% vs -18%, p<0.001).

How They Measured It

VAS pain score, Roland-Morris Disability Questionnaire

Read full study
9

To compare Boswellia with diclofenac for pain relief in knee OA

2011 66 participants 6 months 200 mg Boswellia extract
Human Study RCT Double-Blind Placebo Mixed

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To compare Boswellia with diclofenac for pain relief in knee OA

Dose

200 mg Boswellia extract

Participants

66 OA patients

Duration

6 months

Results

Both treatments equally effective at reducing pain; Boswellia showed superior tolerability profile.

How They Measured It

WOMAC pain, Karnofsky performance scale

Read full study
10

To test Boswellia on exercise-induced muscle soreness and recovery

2018 29 participants 7 days pre/post exercise 2400 mg/day Boswellia serrata
Human Study RCT Positive

Study Type

Randomised, crossover

Purpose

To test Boswellia on exercise-induced muscle soreness and recovery

Dose

2400 mg/day Boswellia serrata

Participants

29 healthy trained males

Duration

7 days pre/post exercise

Results

Significant reduction in perceived muscle soreness and faster recovery vs placebo.

How They Measured It

Perceived soreness VAS, CK levels, recovery time

Read full study
11

To systematically review clinical evidence for Boswellia in musculoskeletal pain conditions

2011 ? participants Various Various
Review/Other Mixed

Study Type

Systematic review

Purpose

To systematically review clinical evidence for Boswellia in musculoskeletal pain conditions

Dose

Various

Participants

Multiple trials

Duration

Various

Results

Strong evidence for Boswellia in osteoarthritis and inflammatory conditions; 7/7 trials showed positive outcomes.

How They Measured It

Systematic review of RCTs

Read full study
12

To evaluate Boswellia in reducing pain from knee OA vs placebo over 4 months

2010 60 participants 4 months 100 mg AKBA-rich Boswellia extract
Human Study RCT Double-Blind Placebo Positive

Study Type

Randomised, double-blind, placebo-controlled

Purpose

To evaluate Boswellia in reducing pain from knee OA vs placebo over 4 months

Dose

100 mg AKBA-rich Boswellia extract

Participants

60 knee OA patients

Duration

4 months

Results

Significant improvement in pain and function from week 4 through week 16 vs placebo (p<0.05).

How They Measured It

WOMAC, patient global assessment

Read full study

Frequently Asked Questions

Common questions about Boswellia research

What does the research say about Boswellia?

There are currently 18 peer-reviewed studies on Boswellia (Boswellia serrata), involving 700 total participants. Research covers Joint health, Inflammation, Pain relief. The overall evidence strength is rated as Very Strong.

How strong is the evidence for Boswellia?

The evidence is currently rated as "Very Strong Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (14 human studies), and reported outcomes.

What health goals has Boswellia been studied for?

Boswellia has been researched for: Joint health, Inflammation, Pain relief. Each area has its own body of evidence which you can explore in the study breakdowns above.

Are the studies on Boswellia based on human trials?

Yes, 14 out of 18 studies are human trials. Human trials carry more weight in our evidence scoring system.