Bibhitaki
Research reviewed: Up until 03/2026
Bibhitaki (Terminalia bellirica (Bahera / Belleric Myrobalan)) is a dietary supplement with 8 published peer-reviewed studies involving 64 participants, researched for Antimicrobial & Antioxidant, Pharmacology & Clinical Applications.
Evidence at a Glance
Strength is scored by study design, sample size, study type, and outcomes
Antimicrobial & Antioxidant
ModeratePharmacology & Clinical Applications
WeakResearch Visualised
Visual breakdown of the clinical data.
Study Quality Breakdown
What types of studies were conducted
Participants Per Study
Larger samples = more reliable results
Research Timeline
When the studies were published
All Studies
Detailed breakdown of each trial. Click to expand.
Antimicrobial & Antioxidant
Antibacterial activity of T. bellirica against MDR bacteria
Study Type
In vitro antimicrobial study
Purpose
Antibacterial activity of T. bellirica against MDR bacteria
Dose
Fruit extract at various concentrations
Participants
In vitro microbiological study
Duration
N/A
Results
Broad-spectrum antibacterial activity against MDR clinical isolates including MRSA and E. coli. High antioxidant activity documented. Non-toxic to mammalian cells at effective concentrations.
How They Measured It
MIC, MBC, disk diffusion against MDR clinical isolates; DPPH antioxidant
T. bellirica as Triphala component against salivary S. mutans
Study Type
Clinical oral health study
Purpose
T. bellirica as Triphala component against salivary S. mutans
Dose
T. bellirica extract mouthwash
Participants
60 dental patients
Duration
2 weeks
Results
T. bellirica component of Triphala significantly reduced oral bacterial counts comparable to chlorhexidine.
How They Measured It
Salivary S. mutans counts, plaque index
Antioxidant and antiproliferative effects of T. bellirica fruit fractions
Study Type
Antioxidant and anticancer study
Purpose
Antioxidant and antiproliferative effects of T. bellirica fruit fractions
Dose
Various solvent fractions
Participants
In vitro cell studies
Duration
N/A
Results
Potent antioxidant and significant antiproliferative activity against multiple cancer cell lines. Gallic acid, ellagic acid, and chebulagic acid primary active compounds.
How They Measured It
DPPH, FRAP, ABTS; MTT assay against cancer cell lines
Pharmacology & Clinical Applications
Review of T. bellirica health benefits and pharmacological activities
Study Type
Comprehensive systematic review
Purpose
Review of T. bellirica health benefits and pharmacological activities
Dose
Various
Participants
Review
Duration
Various
Results
Antioxidant, anti-inflammatory, antimicrobial, antiviral, immunomodulatory, antiplatelet, bronchodilatory, antidiarrheal, hepatoprotective, antidiabetic, and anticancer activities. Gallic and ellagic acid key bioactives.
How They Measured It
Systematic literature review of in vitro, in vivo, and clinical studies
Antidiabetic and antioxidant effects of T. bellirica extract
Study Type
Antidiabetic study
Purpose
Antidiabetic and antioxidant effects of T. bellirica extract
Dose
200-400mg/kg extract
Participants
Diabetic animal model
Duration
4 weeks
Results
Significantly reduced blood glucose and improved antioxidant status. Partial preservation of beta-cell architecture confirmed.
How They Measured It
FBS, PPBS, HbA1c, pancreatic histology
T. bellirica bronchodilatory effects in respiratory disease model
Study Type
Bronchodilatory study
Purpose
T. bellirica bronchodilatory effects in respiratory disease model
Dose
200mg/kg extract
Participants
Animal respiratory model
Duration
Acute
Results
Significant bronchodilatory activity and reduced histamine-induced bronchoconstriction. Beta-adrenergic mechanism supports traditional use in asthma.
How They Measured It
Airway resistance, smooth muscle relaxation, histamine-induced bronchoconstriction
T. bellirica hepatoprotective effects against CCl4 liver injury
Study Type
Hepatoprotective study
Purpose
T. bellirica hepatoprotective effects against CCl4 liver injury
Dose
100-200mg/kg extract
Participants
CCl4 hepatotoxicity model
Duration
7 days
Results
Significantly reduced liver enzymes and preserved normal liver histology. Hepatoprotective activity via antioxidant and anti-inflammatory tannin properties.
How They Measured It
ALT, AST, bilirubin, histopathology
Characterise antimicrobial compounds of T. bellirica and antibiotic synergy
Study Type
Phytochemical and antimicrobial study
Purpose
Characterise antimicrobial compounds of T. bellirica and antibiotic synergy
Dose
Methanolic extract
Participants
In vitro microbiological study
Duration
N/A
Results
LC-MS identified gallic acid, ellagic acid, and chebulic acid as primary antimicrobial compounds. Additive interactions with conventional antibiotics demonstrated.
How They Measured It
LC-MS characterisation, MIC, FIC indices
Frequently Asked Questions
Common questions about Bibhitaki research
There are currently 8 peer-reviewed studies on Bibhitaki (Terminalia bellirica (Bahera / Belleric Myrobalan)), involving 64 total participants. Research covers Antioxidant & anti-aging, Antimicrobial, Respiratory health and 1 more areas. The overall evidence strength is rated as Moderate.
The evidence is currently rated as "Moderate Evidence". This rating is based on study design quality (randomisation, blinding, placebo controls), sample sizes, study types (1 human study), and reported outcomes.
Bibhitaki has been researched for: Antioxidant & anti-aging, Antimicrobial, Respiratory health, Digestive & liver health. Each area has its own body of evidence which you can explore in the study breakdowns above.
Yes, 1 out of 8 studies are human trials. Human trials carry more weight in our evidence scoring system.
